Abstract #4167
Quantitative Magnetic Resonance Imaging for Evaluation of ACL Injuries: a pilot multicenter study
Keiko Amano 1 , Valentina Pedoia 2 , Drew A Lansdown 1 , Cory Wyatt 2 , Narihiro Okazaki 2 , Favian Su 2 , Dragana Savic 2 , Kimberly Amrami 3 , Matthew Frick 4 , Joel Felmlee 3 , Matthew F Koff 5 , Aaron Krych 6 , Hollis Potter 5 , C. Benjamin Ma 1 , Scott Rodeo 7 , Xiaojuan Li 2 , and Sharmila Majumdar 2
1
Department of Orthopaedic Surgery,
University of California, San Francisco, San Francisco,
California, United States,
2
Department
of Radiology, University of California, San Francisco,
San Francisco, California, United States,
3
Department
of Radiology, Mayo Clinic, Minnesota, United States,
4
Radiology,
Mayo Clinic, Minnesota, United States,
5
Department
of Radiology, Hospital for Special Surgery, New York,
United States,
6
Department
of Orthopaedic Surgery, Mayo Clinic, Minnesota, United
States,
7
Department
of Orthopaedic Surgery, Hospital for Special Surgery,
New York, United States
We present the feasibility of detecting cartilage
degeneration using T1ρ and T2 in ACL-injured patients in
a multicenter study. MRIs of 37 patients with ACL
injuries were obtained at three institutions after
injury and prior to surgery. Two healthy volunteers were
scanned at all sites for reliability testing. T1ρ and T2
values were computed with an in-house Matlab program.
Mean inter-site differences were between 0.8-1.6ms for
the volunteers, and mean relaxation times were
significantly higher on the injured knee. These data
indicate good reproducibility across the three sites,
and demonstrates the feasibility of expanding this
technology to multiple institutions.
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