The value of BOLD-MRI in early diagnosis of osteonecrosis of the femoral Head in patients with steroid treatment

Patients who require long-term steroid use are at high risk for occurrence of osteonecrosis. Early diagnosis of this complication is essential as the prognosis is affected by the stage of the disease. However, there is no consensus on whether screening of bone necrosis should be performed for long-term glucocorticoid. Magnetic resonance imaging (MRI) is more sensitive than plain film for diagnosing early-stage bone necrosis [1]. Traditionally functional magnetic resonance imaging (fMRI) using blood oxygenation level-dependent (BOLD) contrast has appeared to measure vascular oxygenation change due to neuron activity. This study attempted to compare BOLD-MRI with conventional MRI sequence on determining the onset of osteonecrosis of the femoral head following steroid-related osteonecrosis.

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