Abstract #4225
Evaluation of the applicability of iGagCESL and gagCEST on both cartilage and disc at 3T
Wen Ling 1 , Nam Vo 2 , Gwendolyn A. Sowa 2 , James Kang 3 , and Kyongtae Ty Bae 1
1
Radiology Department, University of
Pittsburgh Medical Center, Pittsburgh, PA, United
States,
2
Department
of Orthopedic Surgery, University of Pittsburgh Medical
Center, PA, United States,
3
Department
of Orthopedic Surgery, University of Pittsburgh Medical
Center, Pittsburgh, PA, United States
The applicability of recently proposed iGagCESL on both
cartilage and intervertebral disc at 3T has been
evaluated by 3-pool Bloch simulation and in vivo human
data (n=3), along with gagCEST. iGagCESL and gagCEST
give rise to similar contrast, ~1% for cartilage and ~5%
for disc, at 3T; but preserve more than10 times higher
signal intensity than gagCEST. For comparison, same
metrics are used for both simulation and data
acquisition. Along with its additional advantages,
iGagCESL is a much superior method on 3T scanner with
3~5 minutes of scan time.
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