Triple-echo steady state T2 mapping and high resolution axonal bundle assessment of the median nerve in healthy volunteers and patients with carpal tunnel syndrome at 7Tesla
Georg Riegler 1 , Gregor Drlicek 1 , Claudia Kronnerwetter 1 , Rahel Heule 2 , Oliver Bieri 2 , Benedikt Hager 1 , Peter Br 1 , and Siegfried Trattnig 1
MR Centre of Excellence, Dept. of Biomedical
Imaging and Image-Guided Therapy, Medical University
Vienna, Vienna, Vienna, Austria,
of Radiology, Division of Radiological Physics,
University of Basel Hospital, Basel, Switzerland
To determine T2 values of the median nerve with TESS and
the numbers of fascicles with a PD-TSE-fat-sat in
healthy volunteers and patients with
carpal-tunnel-syndrome at 7-Tesla. Six volunteers and
three patients were included. Axial-PD-TSE-fat-sat and
axial-3D-TESS were performed. Two reader assessed T2
values and fascicles. Mean T2 values of patients were
significantly higher for the median nerve in comparison
to healthy subjects (P = 0.008) with an ICC of 0.97.
Median of fascicle count was 19 in all subjects with an
ICC of 0.81. Axial-PD-TSE-fat-sat and axial-3D-TESS
provides fast and reliable morphological and biochemical
assessment of the median nerve.
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