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Abstract #4226

Triple-echo steady state T2 mapping and high resolution axonal bundle assessment of the median nerve in healthy volunteers and patients with carpal tunnel syndrome at 7Tesla

Georg Riegler 1 , Gregor Drlicek 1 , Claudia Kronnerwetter 1 , Rahel Heule 2 , Oliver Bieri 2 , Benedikt Hager 1 , Peter Br 1 , and Siegfried Trattnig 1

1 MR Centre of Excellence, Dept. of Biomedical Imaging and Image-Guided Therapy, Medical University Vienna, Vienna, Vienna, Austria, 2 Department of Radiology, Division of Radiological Physics, University of Basel Hospital, Basel, Switzerland

To determine T2 values of the median nerve with TESS and the numbers of fascicles with a PD-TSE-fat-sat in healthy volunteers and patients with carpal-tunnel-syndrome at 7-Tesla. Six volunteers and three patients were included. Axial-PD-TSE-fat-sat and axial-3D-TESS were performed. Two reader assessed T2 values and fascicles. Mean T2 values of patients were significantly higher for the median nerve in comparison to healthy subjects (P = 0.008) with an ICC of 0.97. Median of fascicle count was 19 in all subjects with an ICC of 0.81. Axial-PD-TSE-fat-sat and axial-3D-TESS provides fast and reliable morphological and biochemical assessment of the median nerve.

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