Abstract #4304
Magnetic Resonance Spectroscopy in the Motor and Sensory Cortices following Surgery for Cervical Spondylotic Myelopathy
Sandy Goncalves 1,2 , Todd K Stevens 2 , Robert Bartha 1,2 , and Neil Duggal 1,3
1
Medical Biophysics, Western University,
London, Ontario, Canada,
2
Centre
for Functional and Metabolic Mapping, Robarts Research
Institute - Western University, London, Ontario, Canada,
3
Clinical
Neurological Sciences, University Hospital - London
Health Sciences Centre, London, Ontario, Canada
Surgical outcome for patients suffering from cervical
spondylotic myelopathy (CSM) is unpredictable with
varying motor and sensory symptom recovery. We show that
absolute NAA levels are lower in CSM patients compared
to controls in motor and sensory cortex and that
following spinal decompression surgery absolute NAA
levels decrease in a similar temporal pattern but in the
opposite direction as clinical motor and sensory
function. This finding suggests that low NAA levels may
be a benefit for functional recovery although the neural
mechanisms involved have not been elucidated.
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