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Abstract #4356

Quantitative spin echo R 2 and brain atrophy measurements for subcortical grey matter in patients with multiple sclerosis: A 2-year longitudinal study

Md Nasir Uddin 1 , R Marc Lebel 1 , Peter Seres 1 , Gregg Blevins 2 , and Alan H Wilman 1

1 Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada, 2 Division of Neurology, University of Alberta, Edmonton, Alberta, Canada

Abnormal iron accumulation in subcortical grey matter is a consistent finding in patients with multiple sclerosis. We demonstrate the time course of spin echo transverse relaxation rate R 2 and brain atrophy in subcortical grey matter and their relationship with multiple sclerosis disease severity using 4.7 T over two years.

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