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Abstract #4388

Association between texture feature ratios and patient survival in glioblastoma

Joonsang Lee 1 , Rajan Jain 2 , Kamal Khalil 3 , Brent Griffith 3 , Ryan Bosca 4 , Ganesh Rao 5 , and Arvind Rao 1

1 Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States, 2 Radiology, New York University School of Medicine, Langone Medical Center, New York, NY, United States, 3 Radiology, Henry Ford Hospital, Detroit, MI, United States, 4 Medical Physics, University of Wisconsin, Madison, WI, United States, 5 Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, United States

The purpose of this study was to investigate the association of the perfusion MRI textural feature ratios with overall survival rates of patients with GBM. Our study presents the results of an exploratory study demonstrating the relationship of texture feature ratios from one- and two-dimensional texture features as well as kinetic texture features with survival in patients with GBM. These findings suggest that texture feature ratios from perfusion MRI data are a promising method as a clinical prognostic tool.

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