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Abstract #4399

Investigation of Vigilance and Working Memory Impairment in Sport Related Concussion Patients with functional MRI

Binjian Sun 1 , Thomas G Burns 1 , Tricia Z King 2 , Laura L Hayes 1 , Ana Arenivas 3 , Susan McManus 1 , Kim E Ono 1 , and Richard A Jones 1,4

1 Children's Healthcare of Atlanta, Atlanta, GA, United States, 2 Georgia State University, Atlanta, GA, United States, 3 Kennedy Krieger Institute, Baltimore, MD, United States, 4 Emory University, Atlanta, GA, United States

Sports Related Concussion (SRC) is a mild form of head trauma, which has been shown to primarily affect brain function rather than structure. In the current study, we used a N-Back fMRI experiment to compare the fMRI results in the acute and delayed phases of recovery from SRC with those from matched normal controls. Our results show that the acute phase of SRC reduces BOLD activation in both vigilance and working memory tasks. It also suggests that SRC induced impairment may largely recover after a relatively short period of time.

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