Abstract #4426
Cervical myelopathy patient follow-up after decompressive surgery using diffusion tensor imaging (DTI) and inhomogeneous magnetization transfer (ihMT): preliminary application and results
Manuel Taso 1,2 , Olivier M. Girard 3,4 , Guillaume Duhamel 3,4 , Thorsten Feiweier 5 , Pierre-Jean Arnoux 2 , Maxime Guye 3,4 , Jean-Philippe Ranjeva 3,4 , Kathia Chaumoitre 6 , Pierre-Hugues Roche 7 , and Virginie Callot 3,4
1
CRMBM-CEMEREM UMR 7339, Aix-Marseille
Universit, CNRS, Marseille, France,
2
LBA
UMR T 24, Aix-Marseille Universit, IFSTTAR, Marseille,
France,
3
CRMBM
UMR 7339, Aix-Marseille Universit, CNRS, Marseille,
France,
4
CEMEREM,
Pole d'imagerie mdicale, Hopital la Timone, AP-HM,
Marseille, France,
5
Siemens
AG, Healthcare, Erlangen, Germany,
6
Service
de radiologie, Hopital Nord, Pole d'imagerie mdicale,
AP-HM, Marseille, France,
7
Service
de Neurochirurgie,Trauma Center, Hopital Nord, AP-HM,
Marseille, France
Cervical myelopathy diagnosis and management in clinical
practice still lacks of objective markers of potential
surgery outcome. Therefore, we applied a multimodal MRI
protocol, combining DTI (known to be more predictive of
surgical outcome than the sole presence of T2
hyperintensity) and inhomogeneous magnetization transfer
(ihMT, myelin-specific technique) to 2 patients before
and 3 months after decompressive surgery. We observed
both metrics evolution after surgery and neurological
function evolution to see whether this multimodal
protocol could help in understanding the evolutive
pattern of the disease after surgery. Longitudinal
follow-up until 1year post-surgery will help in
answering the raised question.
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