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Abstract #4445

Velocity phase imaging with simultaneous multi-slice EPI reveals respiration driven motion in spinal CSF.

Alexander Beckett 1,2 , Liyong Chen 1,2 , Ajay Verma 3 , and David A Feinberg 1,2

1 Helens Wills Neuroscience Institute, University of California, Berkeley, CA, United States, 2 Advanced MRI Technology, Sebastopol, CA, United States, 3 Biogen Idec, MA, United States

Previous research has indicated that respiratory modulations can influence changes in the velocity of CSF flow in the brain and spine. We use simultaneous multi-slice EPI to measure changes in CSF velocity in multiple levels of the spine simultaneously, and show modulations in velocity at the same frequency as respiration. Respiratory modulations are also seen in non-spine (kidney) ROIs, with a phase opposite to that of the spinal modulations.

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