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Abstract #4454

T1ρ-mapping of the heart in a single breath-hold

Joep van Oorschot 1 , Hamza El Aidi 1 , Fredy Visser 2 , Peter Luijten 1 , Tim Leiner 1 , and Jaco Zwanenburg 1

1 University Medical Center Utrecht, Utrecht, Utrecht, Netherlands, 2 Philips Healthcare, Best, Noord-Brabant, Netherlands

T1ρ-mapping shows promising results for the endogenous detection of myocardial fibrosis. A T1ρ-map can be obtained by multiple T1ρ-weighted images with different spin-lock (SL) preparation times. We propose a cardiac T1ρ-mapping method in a single breath-hold. Five healthy volunteers and 2 patients with chronic myocardial infarction were scanned. T1ρ-mapping was performed by acquiring 5 images with different SL preparation times (SL = 0, 10, 20, 30, 40 ms). High resolution T1ρ-maps were successfully acquired in all subjects. The mean T1ρ-relaxation time was 52.73 ms. Coefficient of repeatability in the healthy subjects was 3.74 ms, and in infarct patients 4.59 ms.

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