Abstract #4470
Assessment of diffuse ventricular fibrosis in atrial fibrillation using extracellular volume fraction mapping: initial study
Lei Zhao 1 , Xiaohai Ma 1 , Songnan Li 2 , Tianjing Zhang 3 , Jing An 3 , Greiser Andreas 4 , and Zhanming Fan 1
1
Radiology, Anzhen Hospital, Capital Medical
University, Beijing, Beijing, China,
2
Cardiology,
Anzhen Hospital, Capital Medical University, Beijing,
Beijing, China,
3
MR
Collaborations NE Asia, Siemens Healthcare, Beijing,
China, Beijing, China,
4
Siemens
Healthcare, Erlangen, Germany
Unlike focal fibrosis, diffuse myocardial fibrosis is
not visualized on delayed enhancement magnetic resonance
imaging (MRI), but can be quantified with extracellular
volume fraction (ECV) mapping. In atrial fibrillation
(AF), it may be induced by arrhythmia or reflect
pre-existing cardiomyopathy. Ten subjects (8 persistent
AF patients and 2 controls) underwent cardiac MR
examination which included T1 mapping sequence. Our
results reveal that ECV mapping identifies diffuse LV
fibrosis in patients with AF.
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