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Abstract #4469

Left atrial strain is correlated to atrial fibrosis by late gadolinium enhancement, in an AF population.

Dana C Peters 1 , Daniel Cornfeld 1 , Albert J Sinusas 2 , James S Duncan 1 , Xenios Papademetris 1 , Karl Grunseich 1 , and Sudhakar Chelikani 1

1 Radiology, Yale School of Medicine, New Haven, CT, United States, 2 Cardiology, Yale School of Medicine, New Haven, CT, United States

We tested the hypothesis that left atrial strain was inversely correlated to atrial fibrosis. Left atrial strain was assessed using 2-chamber and 4-chamber cine images in sixteen patients with AF, and 13 control patients, using atrial contouring and a point-matching algorithm. Left atrial late gadolinium enhancement (LGE) was also assessed to obtain a fibrosis score. Average 4-chamber and 2-chamber strains were inversely correlated to the extent of atrial fibrosis in AF subjects, but not in controls. Regional strains also showed strong correlations to LGE.

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