Abstract #4474
Multi-slice Excitation with MRI Tagging for Single Breath hold Estimates of Left Ventricular Rotational Mechanics
Zhe Wang 1,2 , Ziwu Zhou 1,2 , Yi Wang 3 , Peng Hu 1,2 , and Daniel B. Ennis 1,2
1
Radiological Science, University of
California, Los Angeles, CA, United States,
2
Bioengineering,
University of California, Los Angeles, CA, United
States,
3
Neurology, University of California,
Los Angeles, CA, United States
Current clinical protocols for measuring LV twist
require two separate breath holds to acquire tagged
images at the LV apex and LV base, which subjects
estimates of LV twist to breath hold differences.
Multi-slice excitation (CAIPIRINHA) permits combining
these two acquisitions into a single scan. We
implemented the CAIPIRINHA technique with a tagging
sequence, acquired data in five healthy volunteers, and
compare the results with traditional two breath-hold LV
twist results. Linear regression shows a high
correlation between the two (r=0.99) and LV twist
Bland-Altman result shows a small bias of 0.21 with
narrow 95% confident intervals of [-0.47, 0.89].
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