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Abstract #4485

Prospectively Accelerated CMR First-pass Perfusion Imaging in Patients with Suspected Heart Disease

Xiao Chen 1 , Michael Salerno 2,3 , Christopher M. Kramer 3,4 , Bhairav B. Mehta 1 , Yang Yang 1 , Peter Shaw 4 , and Frederick H. Epstein 1

1 Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 2 Radiology, University of Virginia, Charlottesville, VA, United States, 3 Cardiology, University of Virginia, Charlottesville, VA, United States, 4 Medicine, Cardiovascular Medicine, University of Virginia, Charlottesville, VA, United States

First-pass cardiac perfusion MRI demands fast imaging techniques to achieve high spatial resolution and coverage within a small acquisition window. We recently developed a CS method BLOSM to accelerate first-pass perfusion with respiratory motions, and demonstrated the advantages of BLOSM using retrospectively-undersampled first-pass data. In the present study, we aimed to evaluate prospectively-accelerated BLOSM first-pass images in patients with suspected heart disease. Using prospectively accelerated data, BLOSM showed improved reconstruction quality compared to k-t SLR. BLOSM may provide clinically acceptable image quality at higher acceleration rates such as 6, even with the presence of respiratory motion.

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