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Abstract #4486

A Novel Fully Automatic Motion Correction Scheme for Cardiac Perfusion MR Images Using Group-wise Non-rigid Registration

Sandeep Kaushik 1 , Dattesh Shanbhag 1 , Anne Menini 2 , Sheshadri Thiruvenkadam 1 , Stephanie Reiter 3 , Tobias Heer 3 , Gnter Pilz 3 , and Anja Brau 4

1 Medical Image Analysis Lab, GE Global Research, Bangalore, Karnataka, India, 2 GE Global Research, Garching, Bavaria, Germany, 3 Department of Cardiology, Clinic Agatharied Academic Teaching Hospital, University of Munich, Hausham, Bavaria, Germany, 4 GE Healthcare, Garching, Bavaria, Germany

Cardiac perfusion MRI (PWI) scans are typically riddled with heart motion due to scan times too long for breath hold. Non-rigid registration (NRR) algorithms are often used for motion correction. In this work, a group-wise NRR algorithm for motion correction of cardiac PWI images is proposed. Signal intensity variations due to contrast flow can potentially distort and introduce undesirable intensity changes in NRR output. This has been addressed using an intensity normalization scheme. Temporal filter post-processing has been used to eliminate the residual motion. Resulting contrast curves demonstrate time course conformity as validated against ground truth contrast curves.

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