FLASH Proton Density Imaging for Improved Surface Coil Intensity Correction in Quantitative and Semi-Quantitative SSFP Myocardial Perfusion Imaging

Perfusion scans preceded by both FLASH and SSFP-PD frames from 10 patients with no myocardial infarction were analyzed semi-quantitatively and quantitatively. Low flip-angle SSFP protocol exhibited severe ghosting artifacts in 6 of 10 subjects. These artifacts lead to errors in quantitative perfusion maps and semi-quantitative perfusion indexes. They can be severe enough to cause false positives diagnoses. Using FLASH-PD frames as input for the surface coil intensity correction (SCIC) improved the homogeneity of perfusion measurements. Thus, FLASH PD images are recommended for SCIC of SSFP perfusion images in place of low flip angle SSFP PD images.

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