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Abstract #4515

Positive contrast high-resolution 3D-cine imaging of the cardiovascular system in small animals using a UTE sequence and iron nanoparticles at 4.7, 7 and 9.4 T

Aurlien Julien Trotier 1 , William Lefrancois 1 , Kris Van Renterghem 1 , Jean-Michel Franconi 1 , Eric Thiaudire 1 , and Sylvain Miraux 1

1 RMSB-UMR5536, CNRS - Universit de Bordeaux, Bordeaux, Aquitaine, France

To show that 3D sequences with ultra-short echo times (UTEs) can generate a positive contrast whatever the magnetic field (4.7, 7 or 9.4 T) and whatever Ultra Small Particles of Iron Oxide (USPIO) concentration injected and to use it for 3D time-resolved imaging of the murine cardiovascular system with high spatial and temporal resolutions. This approach might be useful to measure the functional cardiac parameters or to assess anatomical modifications to the blood vessels in cardio-vascular disease models.

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