Positive contrast high-resolution 3D-cine imaging of the cardiovascular system in small animals using a UTE sequence and iron nanoparticles at 4.7, 7 and 9.4 T
Aurlien Julien Trotier 1 , William Lefrancois 1 , Kris Van Renterghem 1 , Jean-Michel Franconi 1 , Eric Thiaudire 1 , and Sylvain Miraux 1
RMSB-UMR5536, CNRS - Universit de Bordeaux,
Bordeaux, Aquitaine, France
To show that 3D sequences with ultra-short echo times
(UTEs) can generate a positive contrast whatever the
magnetic field (4.7, 7 or 9.4 T) and whatever Ultra
Small Particles of Iron Oxide (USPIO) concentration
injected and to use it for 3D time-resolved imaging of
the murine cardiovascular system with high spatial and
temporal resolutions. This approach might be useful to
measure the functional cardiac parameters or to assess
anatomical modifications to the blood vessels in
cardio-vascular disease models.
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