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Abstract #4530

Unwrapping-based fat-suppression method for imaging scar using bipolar dual-echo acquisition

Junmin Liu 1 , Dana C Peters 2 , and Maria Drangova 1,3

1 Imaging Research Laboratories, Robarts Research Institute, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontraio, Canada, 2 Department of Diagnostic Radiology, Yale Medical School, New Haven, Connecticut, United States, 3 Department of Medical Biophysics, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada

Dixon techniques to suppress fat signal are sometimes required for assessment of fibrosis/scar with late gadolinium enhancement (LGE). Among Dixon LGE techniques, the bipolar dual-echo technique is intrinsically the fastest, and is thus optimal for high-resolution LGE imaging. However, perfect fat-water separation with bipolar dual-echo acquisition is still very difficult to obtain. We extended a recently published (mono-polar multi-echo) non-iterative phase-unwrapping-based field mapping method (B0-NICE) to this challenging case. The method is tested in three human subjects with left atrial LGE and the results are compared with those obtained using an established region-growing algorithm.

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