Abstract #4531
T1-mapping based synthetic phase-sensitive inversion recovery imaging for the accurate quantification of myocardial late gadolinium enhancement
Akos Varga-Szemes 1 , Rob J van der Geest 2 , Bruce Spottiswoode 3 , Giuseppe Muscogiuri 1,4 , Carlo N De Cecco 1,4 , Pal Suranyi 1 , Wolfgang G Rehwald 3,5 , and U. Joseph Schoepf 1
1
Medical University of South Carolina,
Charleston, SC, United States,
2
Leiden
University Medical Center, Leiden, Netherlands,
3
Siemens
Medical Solutions, Chicago, IL, United States,
4
University
of Rome Sapienza, Rome, Italy,
5
Duke
Cardiovascular Magnetic Resonance Center, Durham, NC,
United States
We evaluated the feasibility of myocardial infarct
quantification using synthetic phase-sensitive inversion
recovery (PSIR) images. Patients underwent conventional
PSIR and prototype modified look-locker IR (MOLLI)-based
T1 acquisitions. Synthetic IR images were
retrospectively calculated based on the voxel-by-voxel
T1 values using an in-house developed application
integrated in the Mass Research Software. Late
gadolinium enhancement (LGE) measured by conventional
and synthetic PSIR techniques showed no statistical
difference indicating that LGE quantification using
synthetic PSIR images is feasible. With the increasing
availability of T1-mapping, the need for conventional
PSIR images could be omitted, resulting in a significant
reduction in scanner time.
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