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Abstract #4531

T1-mapping based synthetic phase-sensitive inversion recovery imaging for the accurate quantification of myocardial late gadolinium enhancement

Akos Varga-Szemes 1 , Rob J van der Geest 2 , Bruce Spottiswoode 3 , Giuseppe Muscogiuri 1,4 , Carlo N De Cecco 1,4 , Pal Suranyi 1 , Wolfgang G Rehwald 3,5 , and U. Joseph Schoepf 1

1 Medical University of South Carolina, Charleston, SC, United States, 2 Leiden University Medical Center, Leiden, Netherlands, 3 Siemens Medical Solutions, Chicago, IL, United States, 4 University of Rome Sapienza, Rome, Italy, 5 Duke Cardiovascular Magnetic Resonance Center, Durham, NC, United States

We evaluated the feasibility of myocardial infarct quantification using synthetic phase-sensitive inversion recovery (PSIR) images. Patients underwent conventional PSIR and prototype modified look-locker IR (MOLLI)-based T1 acquisitions. Synthetic IR images were retrospectively calculated based on the voxel-by-voxel T1 values using an in-house developed application integrated in the Mass Research Software. Late gadolinium enhancement (LGE) measured by conventional and synthetic PSIR techniques showed no statistical difference indicating that LGE quantification using synthetic PSIR images is feasible. With the increasing availability of T1-mapping, the need for conventional PSIR images could be omitted, resulting in a significant reduction in scanner time.

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