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Abstract #0013

Validation of Surface-to-Volume Ratio derived from Oscillating Gradient Spin Echo on a clinical scanner using anisotropic fiber phantoms

Gregory Lemberskiy1, Steven H. Baete1, Martijn A. Cloos1, Dmitry S. Novikov1, and Els Fieremans1

1Radiology, NYU School of Medicine, New York, NY, United States

This work represents the first measurement of S/V on a clinical scanner using OGSE on a well-characterized anisotropic fiber phantom. The S/V measurement is validated externally via non-diffusion metrics (Spin Echo and MR Fingerprinting). Lastly, a comparison of $$$D(\omega)$$$ and $$$D(t)$$$ shows that the effective diffusion time is $$$t_{\rm eff}^{\rm Mitra} = 9/64f = 9/16\cdot t_{\rm eff}$$$ rather than the commonly used $$$t_{\rm eff} = 1/4f$$$.

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