Abstract #0013

Validation of Surface-to-Volume Ratio derived from Oscillating Gradient Spin Echo on a clinical scanner using anisotropic fiber phantoms

Gregory Lemberskiy¹, Steven H. Baete¹, Martijn A. Cloos¹, Dmitry S. Novikov¹, and Els Fieremans¹

¹Radiology, NYU School of Medicine, New York, NY, United States

This work represents the first measurement of S/V on a clinical scanner using OGSE on a well-characterized anisotropic fiber phantom. The S/V measurement is validated externally via non-diffusion metrics (Spin Echo and MR Fingerprinting). Lastly, a comparison of $$$D(\omega)$$$ and $$$D(t)$$$ shows that the effective diffusion time is $$$t_{\rm eff}^{\rm Mitra} = 9/64f = 9/16\cdot t_{\rm eff}$$$ rather than the commonly used $$$t_{\rm eff} = 1/4f$$$.

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