Abstract #0023

Fast frequency–sweep spectroscopic imaging with an ultra-low flip angle

Junyu Guo¹, Zoltan Patay¹, and Wilbrun E. Reddick¹

¹St Jude Children's Research Hospital, Memphis, TN, United States

We present a novel, simple and fast MR spectroscopic imaging technique and show its conceptual validation with simulations and demonstrate proof-of-principle with phantom and human studies. First, compared to the conventional spectroscopic imaging in the time-domain, our method acquires data in the frequency domain, allowing flexible non-uniform sampling to speed up the acquisition. Second, using ultra-small RF pulses offers intrinsic water and fat suppression, greatly simplifying the scanning procedures. Third, this new technique has hundreds of times lower energy deposition than conventional MRI scans. We believe our method could allow spectroscopic imaging to play a larger role in clinical applications.

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