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Abstract #0039

Evaluation of Upper Airway Collapsibility Using Simultaneous Multi-Slice Real-Time MRI

Ziyue Wu1,2, Weiyi Chen1, Michael C.K. Khoo1, Sally L. Davidson Ward3, and Krishna S. Nayak1

1University of Southern California, Los Angeles, CA, United States, 2Alltech Medical Systems, Solon, OH, United States, 3Children's Hospital Los Angeles, Los Angels, CA, United States

We present a method for simultaneous multi-slice airway collapsibility measurement based on sparse golden-angle radial CAIPIRINHA, with acceleration factor up to 33.3. We present data from patients with obstructive sleep apnea and normal controls. One interesting finding is that a narrower airway site does not always correspond to higher collapsibility. This finding may be of interest to sleep surgeons. Our results also suggest that both compliance and Pclose were significantly different between healthy controls and OSA patients (P<0.001), and both measures can potentially serve as biomarkers.

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