Abstract #0038

xSPEN: Single-shot magnetic resonance imaging with exceptional resilience to field heterogeneities

Zhiyong Zhang¹, Amir Seginer¹, and Lucio Frydman¹

¹Chemical Physics, Weizmann Institute of Science, Rehovot, Israel

Single-shot MRI has been constrained to acquisitions in quality magnets and homogeneous tissues. The present study introduces a methodology that can deliver such images with good SNR, under much poorer field and/or multiple shift conditions. These capabilities are achieved based on new principles whereby images are read using field gradients that are not applied along the direction being encoded. This enables one to accommodate shifts/inhomogeneities into the single-scan image generation protocol, without suffering from miss-registrations, without requiring a priori information for post-acquisition corrections, and without demanding specialized instrumentation. This enables new single-shot investigations that have hitherto escaped from MRI’s scope.

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