Sriranga Kashyap1, Dimo Ivanov1, Martin Havlíček1, Benedikt A Poser1, and Kâmil Uludağ1
Cortical-depth dependent fMRI usually relies on
the definition of depths on an anatomical image (eg. MPRAGE). The geometric dissimilarities
of the functional compared to the anatomical data require further spatial
processing of the functional data to ensure good co-registration. We propose an
alternative approach that uses an optimised inversion-recovery EPI derived T1
image, whose resolution and readout, hence distortions, are identical to that
of the functional data, in order to delineate cortical depths. As a result, the
cortical-depth specific fMRI data can be analysed in the native space without
any spatial confounds stemming from distortion correction and inaccurate
registration.
