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Abstract #0071

Distortion-matched T1-maps and bias-corrected T1w-images as anatomical reference for submillimeter-resolution fMRI

Wietske van der Zwaag1, Pieter Buur1, Maarten Versluis2, and José P. Marques3

1Spinoza Centre for Neuroimaging, Amsterdam, Netherlands, 2Philips Healthcare, Best, Netherlands, 3Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands

Achieving sufficiently good quality co-registration between the anatomical and functional images is currently a large stumbling block for laminar fMRI. Here, we present a distortion-matched T1weighted/T1-estimation mapping approach using two 3D-EPI readouts per inversion, following the MP2RAGE signal combination. 0.7mm isotropic T1 data with matching distortions to a 0.7mm isotropic fMRI protocol can be acquired in less than two minutes.

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