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Abstract #0074

Longitudinal Evaluation of Cartilage Component of Matrix-Associated Autologous Chondrocyte Transplants using Biochemical MR Imaging

Xian Xu1, Ningyu An1, Panli Zuo2, and Esther Raithel3

1Department of Radiology, Chinese PLA General Hospital, Beijing, China, People's Republic of, 2Siemens Healthcare, MR Collaborations NE Asia, Beijing, China, People's Republic of, 3Siemens Healthcare GmbH, Berlin, Germany

This study combined T2 mapping and delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) technique to evaluate the repair cartilage tissue after Matrix-associated autologous chondrocyte implantation (MACI). We found that the T2 and ΔR1 values of the repair tissue were significantly higher than the native tissue at 1, 3 and 6 months after MACI, but showed a downward trend and showed no difference with native tissue at 12 months, which suggested that the integrity of the collagen and GAG of repair tissue was similar to native cartilage.

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