Abstract #0074

Longitudinal Evaluation of Cartilage Component of Matrix-Associated Autologous Chondrocyte Transplants using Biochemical MR Imaging

Xian Xu¹, Ningyu An¹, Panli Zuo², and Esther Raithel³

¹Department of Radiology, Chinese PLA General Hospital, Beijing, China, People's Republic of, ²Siemens Healthcare, MR Collaborations NE Asia, Beijing, China, People's Republic of, ³Siemens Healthcare GmbH, Berlin, Germany

This study combined T2 mapping and delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) technique to evaluate the repair cartilage tissue after Matrix-associated autologous chondrocyte implantation (MACI). We found that the T2 and ΔR1 values of the repair tissue were significantly higher than the native tissue at 1, 3 and 6 months after MACI, but showed a downward trend and showed no difference with native tissue at 12 months, which suggested that the integrity of the collagen and GAG of repair tissue was similar to native cartilage.

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