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Abstract #0080

In vivo assessment of T2* in menisci under loading conditions at 3 Tesla: preliminary results

Vladimir Juras1,2, Lenka Hornakova3, Petr Kubovy3, Daniel Hadraba3,4, Pavel Stursa5, David Gerych3, Pavol Szomolanyi1, Karel Jelen3, and Siegfried Trattnig1,6

1Department of Biomedical Imaging and Image-Guided Therapy, High Field MR Centre, Medical University of Vienna, Vienna, Austria, 2Department of Imaging Methods, Institute for Measurement Science, Bratislava, Slovakia, 3Department of Anatomy and Biomechanics, Faculty Of Physical Education and Sport, Prague, Czech Republic, 4Department of Radiology, Hospital na Homolce, Prague, Czech Republic, 5Academy of Sciences of the Czech Republic, Prague, Czech Republic, 6Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria

Meniscus behavior under loading in vivo has been studied using parametric MR imaging. T2* has been acquired with vTE using very short first TE = 0.8 ms to secure the precise estimation. The knees of the subjects were loaded in situ with custom made compression device and T2* mapping was performed in 5 time points (without loading, and 4 consequent scans under the loading 7 min apart). The increase in T2* was observed in all compartments, significance was found in medial meniscus only. vTE T2* mapping might be a prospective marker for detecting the dynamic response of the meniscal tissue.

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