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Abstract #0079

Local Analysis of T1ρ, T2, and R2–R1ρ Compositional MR Imaging in Patients with ACL Injury Using Voxel-Based Relaxometry

Colin Russell1, Valentina Pedoia1, Keiko Amano1, and Sharmila Majumdar1

1Radiology and Biomedical Imaging, University of California, San Francsico, San Francisco, CA, United States

This multicenter study employs VBR as a novel technique to analyze patients with ACL tears at the time of injury and 6 months after ACL reconstruction. T1ρ and T2 analysis, correlation, and dispersion difference (R2–R1ρ) are three methods employed to highlight significant cartilage changes. The most posterior region of the posterior lateral tibia and the patella indicated partial cartilage recovery 6 months after reconstruction, demonstrated by decreasing T1ρ and T2, decreased T1ρ T2 correlation baseline to 6 months, and dispersion differences (R2–R1ρ). The trochlea displayed symptoms of cartilage degeneration, such as elevated T1ρ and T2 and dispersion differences.

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