Abstract #0085

Identifying carotid plaque inflammation using high and low molecular weight contrast agents

Jason Kraig Mendes¹, Scott McNally¹, Seong-Eun Kim¹, Bradley D. Bolster², Gerald S. Treiman³, and Dennis L. Parker¹

¹Radiology, University of Utah, SLC, UT, United States, ²Siemens Healthcare, SLC, UT, United States, ³Department of Veterans Affairs, SLC, UT, United States

Carotid plaque inflammation can be measured with dynamic contrast enhanced (DCE) MRI and is a marker for plaque instability. Despite this, DCE has not become a clinically viable tool in diagnosing carotid plaque instability and the corresponding stroke risk. The barrier to progress is a DCE protocol meeting requirements for clinical use to monitor medical treatment effect or failure. This project overcomes this barrier by developing a reliable and inclusive dual contrast DCE protocol to identify carotid plaque inflammation.

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