Abstract #0084

Diffusion and perfusion MR imaging indicate inflammation followed by fibrosis in a hepatitis B infected humanized mouse liver model

Prashant Chandrasekharan¹, Dahai Zheng², Kavita Kaur D/O Ranjit Singh¹, Qingfeng Chen², and Kai Hsiang Chuang¹

¹A*STAR, Singapore Bio Imaging Consortium, Singapore, Singapore, ²A*STAR, Institute of Molecular and Cell Biology, Singapore, Singapore

Humanized mouse model of liver infection is essential to understand the role of the immune system during disease progression and therapeutic intervention. In this study we have used MRI functional imaging bio-markers to assess the pathology related to Hepatitis B infection in a humanized mouse liver model.

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