Abstract #0119

Behavioral response time as explained by a fiber-based analysis of generalized fractional anisotropy measured using diffusion spectrum imaging

Kayako Matsuo¹, Yung-Chin Hsu², Yasuo Takehara³, Wen-Yih Isaac Tseng², and Norio Mori¹

¹Dept. Psychiatry, Hamamatsu University School of Medicine, Hamamatsu, Japan, ²Institute of Medical Devices and Imaging System, National Taiwan University College of Medicine, Taipei, Taiwan, ³Dept. Radiology, Hamamatsu University School of Medicine, Hamamatsu, Japan

DSI on a GE 3T was conducted for 22 normal controls to examine the neural basis of the response time (RT). RT was measured outside the scanner using button pressing by left or right hand in response to visual or auditory stimulation. Faster RT was associated with greater GFA of portions near the cortical hand area in the corticospinal tract (CST). Left and right hand specializations were found in the deeper CST. Greater GFA in portions near the cortex in the left auditory radiation was associated with faster RT by visual stimulations, suggesting an influence of language processing speed.

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