Abstract #0133

Quantitative MRI and optoacoustic imaging tracks treatment response in tumor

Prashant Chandrasekharan¹, Ghayathri Balasundaram¹, Amalina Binte Ebrahim Attia¹, Chris Jun Hui Ho¹, Xuan Vinh To¹, Hui Chien Tay¹, Kai Hsiang Chuang¹, and Malini Olivo¹

¹A*STAR, Singapore Bio Imaging Consortium, Singapore, Singapore

Quantification of oxygenation or hypoxia in a tumor plays a key role in the treatment response and the overall survival of glioma patient. This work illustrates a preclinical study with the use of multimodal imaging technique to correlate tumor oxygenation and blood perfusion, as well as to assess the changes involved in the perturbation of the tumor system using a vascular disruptive agent.

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