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Abstract #0146

Intradialytic MRI for the assessment of Cardiovascular Function

Charlotte E Buchanan1,2, Azharuddin Mohammed2, Eleanor F Cox1, Maarten W Taal2, Nicholas M Selby2, Susan T Francis1, and Christopher W McIntyre3

1Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom, 2Division of Medical Sciences and Graduate Entry Medicine, University of Nottingham, Nottingham, United Kingdom, 3Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada

We perform the first study of intradialytic MRI to assess cardiovascular stress during dialysis. A significant reduction in cardiac output (CO), stroke volume (SV) and IVC flux was seen during dialysis. Myocardial strain measures revealed significant stunned segments in the long axis in all individuals. No significant change in coronary artery flow was evident, and both myocardial perfusion and T1 measures in a single short axis slice showed no significant change. The change in CO and SV was negatively correlated with dialysis ultrafiltration volume. This work demonstrates MRI can be used to assess cardiac stress during dialysis.

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