Abstract #0159

Hemodynamic Changes in the Portal Circulation in Living Related Liver Donors, Assessed by 4D flow MRI

Alejandro Roldán-Alzate^1,2, Luis A Fernandez³, Oliver Wieben^2,4, and Scott B Reeder^2,4

¹Mechanical Engineering, University of Wisconsin - Madison, Madison, WI, United States, ²Radiology, University of Wisconsin - Madison, Madison, WI, United States, ³Surgery, University of Wisconsin - Madison, Madison, WI, United States, ⁴Medical Physics, University of Wisconsin - Madison, Madison, WI, United States

The purpose of this study was to evaluate hemodynamic changes in the mesenteric and portal circulation of LDLT donors in response to surgical liver resection. Four living related liver donors were studied. Subjects were imaged using 4D Flow MRI before and after liver resection surgery. Highly patient-specific responses to each surgical procedure were found. The ability to quantify hemodynamic changes in the portal and mesenteric circulation non-invasively demonstrates that 4D flow MRI may be a suitable tool for both surgical planning of LDLT, and for improved understanding of the hemodynamic changes that occur in the liver remnant of the donor.

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