Abstract #0179

Selective in Vivo Bone Imaging with Long-T2 suppressed PETRA MRI

Cheng Li¹, Jeremy F. Magland¹, Xia Zhao¹, Alan C. Seifert², and Felix W. Wehrli¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States, ²Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States

An IR-based long-T2 suppressed PETRA sequence was designed and optimized to image sub-millisecond-T2 tissue components, e.g. collagen-bound bone water. To minimize scan time signal was sampled repeatedly after each inversion with individual excitation flip-angle designed to yield constant short-T2 signal amplitude. A fast non-iterative reconstruction algorithm combined with phase-modulated excitation pulse was applied to minimize image artifacts due to non-uniform excitation profile, allowing for increased flip-angle and higher SNR. Optimized long-T2 suppressed PETRA allows imaging of bone matrix water, opening up new possibilities for anatomic bone imaging at isotropic resolution and quantification in clinically practical scan times.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.