Abstract #0216

Diffusion-weighted MRI using undersampled radial STEAM with iterative image reconstruction

Andreas Merrem¹, Jakob Klosowski¹, Sabine Hofer¹, Klaus-Dietmar Merboldt¹, and Jens Frahm¹

¹Biomedizinische NMR Forschungs GmbH, Max-Planck-Institut für Biophysikalische Chemie, Göttingen, Germany

Single-shot STEAM MRI is a method for black-blood diffusion-weighted imaging where the use of radiofrequency-refocussed echoes leads to no image distortions, no susceptibility artifacts, and no violations of the Carr-Purcell-Meiboom-Gill condition. Despite these favorable properties, clinical applications have been limited by a low signal-to-noise ratio. Here, we demonstrate the development of highly undersampled radial diffusion-weighted single-shot STEAM MRI with iterative reconstruction to achieve acceptable signal-to-noise for studies of the human brain.

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