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Abstract #0267

Assessing longitudinal renal blood flow changes in children following renal replacement therapy using Arterial Spin Labelling MRI

Fábio Nery1, Enrico De Vita2,3, Chris A. Clark1, Isky Gordon1, and David L. Thomas3

1UCL Institute of Child Health, Developmental Imaging and Biophysics Section, LONDON, United Kingdom, 2National Hospital for Neurology and Neurosurgery, Lysholm Department of Neuroradiology, LONDON, United Kingdom, 3UCL Institute of Neurology, Department of Brain Repair and Rehabilitation, LONDON, United Kingdom

Arterial spin labelling (ASL) is a contrast-free MRI technique that allows for the quantitative measurement of organ perfusion. In this study, we non-invasively evaluated renal perfusion changes in sixteen children within the first year following renal replacement therapy using ASL. Each child was scanned in three occasions : (A) immediately post-transplant; (B) “1 month” post-transplant and (C) “1 year” post-transplant. The highest renal cortical blood flow was seen on the first scan in the majority of children while in later scans equilibrium between child and kidney was reached.

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