Abstract #0267

Assessing longitudinal renal blood flow changes in children following renal replacement therapy using Arterial Spin Labelling MRI

Fábio Nery¹, Enrico De Vita^2,3, Chris A. Clark¹, Isky Gordon¹, and David L. Thomas³

¹UCL Institute of Child Health, Developmental Imaging and Biophysics Section, LONDON, United Kingdom, ²National Hospital for Neurology and Neurosurgery, Lysholm Department of Neuroradiology, LONDON, United Kingdom, ³UCL Institute of Neurology, Department of Brain Repair and Rehabilitation, LONDON, United Kingdom

Arterial spin labelling (ASL) is a contrast-free MRI technique that allows for the quantitative measurement of organ perfusion. In this study, we non-invasively evaluated renal perfusion changes in sixteen children within the first year following renal replacement therapy using ASL. Each child was scanned in three occasions : (A) immediately post-transplant; (B) “1 month” post-transplant and (C) “1 year” post-transplant. The highest renal cortical blood flow was seen on the first scan in the majority of children while in later scans equilibrium between child and kidney was reached.

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