Abstract #0272

Kidney diffusion-weighted imaging based on multi-band multi-shot DW-EPI acquisition and multi-band multiplexed sensitivity encoding (MB-MUSE) reconstruction

Hing-Chiu Chang^1,2, Arnaud Guidon³, Mustafa R. Bashir⁴, Dan Xu⁵, Lloyd Estkowski⁶, Ersin Bayram⁷, Allen W. Song², and Nan-Kuei Chen²

¹Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, Hong Kong, ²Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC, United States, ³Global MR Application and Workflow, GE Healthcare, Boston, MA, United States, ⁴Department of Radiology, Duke University Medical Center, Durham, NC, United States, ⁵Global MR Application and Workflow, GE Healthcare, Waukesha, WI, United States, ⁶Global MR Application and Workflow, GE Healthcare, Menlo Park, CA, United States, ⁷Global MR Application and Workflow, GE Healthcare, Houston, TX, United States

DWI has been shown to be useful in characterizing renal carcinoma with quantitative measurement of ADC. However, with echo-planar imaging (EPI) based DWI protocols, the application of body DWI remains limited due to suboptimal EPI image quality. The multi-band multi-shot EPI with multiplexed sensitivity encoding (MB-MUSE) has been developed and shown to be useful in achieving high-resolution and high-quality DWI and DTI of brains, with improved scan throughput. In this study, we propose to use MB multi-shot EPI to acquire kidney DWI data with reduced geometric distortion and bilateral coverage, demonstrating the feasibility of MB multi-shot DWI of body applications.

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