Abstract #0300

Conjoint measure of 3D ASL and 3D APT in the lesion proximal regions for differentiating metastasis tumor from glioblastom

Rui Li¹, Bing Wu², Chien-yuan Lin³, Xin Lou¹, YuLin Wang¹, and Lin Ma¹

¹Department of Radiology, PLA general Hospital, Beijing, China, People's Republic of, ²GE healthcare MR Research China, Beijing, China, People's Republic of, ³GE heathcare Taiwan, Taipei, Taiwan

Differential diagnosis is challenging due to similar appearance using conventional imaging such as T1 contrast enhanced and DWI. In this work, we use the measure of spatially matching 3D arterial spin labeling (ASL) and 3D amide proton transfer (APT) in the lesion proximal regions to differentiate metastasis and glioblastom, in the hypothesis that glioblastom infiltrates into sourrounding tissues whereas metastasis tumors have clear biological boundaries.

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