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Abstract #0318

Characterization of aortic blood flow after aortic valve replacement by 4D flow MRI

Alex S Hong1, Emilie Bollache1, Pim van Ooij1, James C Carr1, Alex J Barker1, Jeremy D Collins1, and Michael Markl2

1Department of Radiology, Northwestern University, Chicago, IL, United States, 2Department of Radiology, Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States

Aortic valve replacement (AVR) is an effective surgical approach to treating aortic valvular disease, but it is unclear if and what type of prosthesis can fully reproduce physiologically normal flow characteristic of a native aortic valve. We utilized 4D flow MRI to systematically compare blood flow in the thoracic aorta in post-AVR (bioprosthetic vs. mechanical) patients and healthy controls. Both bioprosthetic and mechanical valves were found to produce higher peak systolic flow velocities and peak wall shear stress in the ascending aorta than native valves, demonstrating the presence of significant changes in aortic blood flow in AVR patients.

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