Abstract #0323

3D Blood Flow Velocity Distribution in the Normal Aorta: Effect of Age and Gender Across 101 Subjects

Julio Garcia¹, Roel L.F. van der Palen², Alex J. Barker¹, Jeremy D. Collins¹, James C. Carr¹, Joshua Robinson³, Cynthia Rigsby³, and Michael Markl^1,4

¹Radiology, Northwestern University, Chicago, IL, United States, ²Pediatric Cardiology, Leiden University Medical Center, Leiden, Netherlands, ³Department of Medical Imaging, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, United States, ⁴Biomedical Engineering, Northwestern University, Evanston, IL, United States

The systematic characterization of effects in aortic disease patients and healthy controls is important to improve disease diagnosis. 4D flow MRI can be applied for the analysis of altered hemodynamics in cardiovascular disease. However, data analysis can be time consuming and often data are not fully utilized by analysis based on 2D planes. This study aimed to systematically apply flow distribution analysis in the entire volume of the aorta to establish normative reference values across a wide age range from pediatric to adult subjects.

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