Abstract #0324

High Quality Preclinical 4D-Flow Phase Contrast Imaging

Moritz Braig¹, Jochen Leupold¹, Ko Cheng-Wen², Marius Menza¹, Juergen Hennig¹, Jan Korvink³, and Dominik von Elverfeldt¹

¹University Medical Center Freiburg, Freiburg, Germany, ²Dept. Computer Science and Engineering, National Sun Yat-sen University, Kaohsiung, Taiwan, ³Institute of Microstructure Technology, Karlsruhe Institute of Technology, Karlsruhe, Germany

So far preclinical 4D-Flow MRI has not been able to deliver an analysis of complex flow due to low resolution. The presented framework and improvements allow high quality data acquisitions with a reduced measurement time and the possibility to visualize regional flow abnormalities. An automatic magnitude segmentation in every timeframe combines anatomic information with the underlying blood flow showing even small vessels. It will draw new conclusions in mouse models of cardiovascular diseases as a valuable tool for preclinical researchers.

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