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Abstract #0363

Bone Quantitative Susceptibility Mapping using tissue specific R2* and multi-peak fat spectrum to model ultra-short TE gradient echo signal

Alexey V. Dimov1,2, Zhe Liu1,2, Pascal Spincemaille2, and Yi Wang1,2

1Department of Biomedical Engineering, Cornell University, Ithaca, NY, United States, 2Radiology Department, Weill Cornell Medical College, New York, NY, United States

Bone quantitative susceptibility mapping (QSM) using standard IDEAL fat water/signal model often suffers from erroneous labeling of water component. We propose a new field estimation approach incorporating the negligible T2* decay of fat compared to bone water signal, and modeling fat with multiple spectral peaks. This tissue specific R2* multi-peak signal allows robust field mapping from radial ultra-short TE gradient echo data, enabling in vivo bone QSM with consistent high quality.

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