Abstract #0363

Bone Quantitative Susceptibility Mapping using tissue specific R2* and multi-peak fat spectrum to model ultra-short TE gradient echo signal

Alexey V. Dimov^1,2, Zhe Liu^1,2, Pascal Spincemaille², and Yi Wang^1,2

¹Department of Biomedical Engineering, Cornell University, Ithaca, NY, United States, ²Radiology Department, Weill Cornell Medical College, New York, NY, United States

Bone quantitative susceptibility mapping (QSM) using standard IDEAL fat water/signal model often suffers from erroneous labeling of water component. We propose a new field estimation approach incorporating the negligible T2* decay of fat compared to bone water signal, and modeling fat with multiple spectral peaks. This tissue specific R2* multi-peak signal allows robust field mapping from radial ultra-short TE gradient echo data, enabling in vivo bone QSM with consistent high quality.

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