Abstract #0367

Diffusion Tensor Imaging of Human Achilles Tendon by Stimulated Echo RESOLVE (ste-RESOLVE)

Xiang He¹, Kenneth Wengler², Alex C Sacher³, Marco Antonio Oriundo Verastegui¹, Alyssa Simeone⁴, Mingqian Huang¹, Elaine Gould¹, and Mark Schweitzer¹

¹Department of Radiology, Stonybrook University School of Medicine, Stony Brook, NY, United States, ²Department of Biomedical Engineering, Stonybrook University School of Medicine, Stony Brook, NY, United States, ³SUNY Binghamton University, Binghamton, NY, United States, ⁴New York Medical College, Valhalla, NY, United States

Diffusion tensor imaging (DTI) is sensitive to the injury-induced changes on the tendons microstructure. However, conventional spin-echo based DTI techniques often lead to poor tendon MR signal and difficulty on diffusion quantification, mainly due to the short tendon T2/T2* relaxation time constant. In this study, a novel method of combining stimulated-echo based DTI and readout-segmented multi-shot EPI (ste-RESOLVE) has been developed and evaluated. TE value can be as low as 20 ms for b value of 800 s/mm², enabling robust investigation of Achilles tendon microscopic tissue integrity on clinical MR scanners.

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