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Abstract #0367

Diffusion Tensor Imaging of Human Achilles Tendon  by Stimulated Echo RESOLVE  (ste-RESOLVE)

Xiang He1, Kenneth Wengler2, Alex C Sacher3, Marco Antonio Oriundo Verastegui1, Alyssa Simeone4, Mingqian Huang1, Elaine Gould1, and Mark Schweitzer1

1Department of Radiology, Stonybrook University School of Medicine, Stony Brook, NY, United States, 2Department of Biomedical Engineering, Stonybrook University School of Medicine, Stony Brook, NY, United States, 3SUNY Binghamton University, Binghamton, NY, United States, 4New York Medical College, Valhalla, NY, United States

Diffusion tensor imaging (DTI) is sensitive to the injury-induced changes on the tendons microstructure. However, conventional spin-echo based DTI techniques often lead to poor tendon MR signal and difficulty on diffusion quantification, mainly due to the short tendon T2/T2* relaxation time constant. In this study, a novel method of combining stimulated-echo based DTI and readout-segmented multi-shot EPI (ste-RESOLVE) has been developed and evaluated. TE value can be as low as 20 ms for b value of 800 s/mm2, enabling robust investigation of Achilles tendon microscopic tissue integrity on clinical MR scanners.

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