Abstract #0366

Assessment of meniscus with adiabatic $$$T_{1\rho}$$$ and $$$T_{2\rho}$$$ in asymptomatic subjects and patients with early osteoarthritis: Oulu knee osteoarthritis study

Abdul Wahed Kajabi^1,2,3, Victor Casula^2,3, Arttu Peuna^2,3,4, Simo Saarakkala^2,5, Eveliina Lammentausta^3,4, Ali Guermazi⁶, and Miika T. Nieminen^2,3,4

¹Department of Biomedical Engineering, University of Oulu, Oulu, Finland, ²Research Unit of Medical Imaging, Physics and Technology, University of Oulu and Oulu University Hospital, Oulu, Finland, ³Medical Research Center, University of Oulu and Oulu University Hospital, Oulu, Finland, ⁴Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland, ⁵Department of Medical Technology, Institute of Biomedicine, University of Oulu, Oulu, Finland, ⁶Department of Radiology, Boston University School of Medicine, MA, MA, United States

Evaluation of meniscal degeneration in asymptomatic subjects and patients with early osteoarthritis (KL = 1,2) was performed using adiabatic $$$T_{1\rho}$$$ and $$$T_{2\rho}$$$ ($$$AdT_{1\rho}$$$ and $$$AdT_{2\rho}$$$, respectively) measurements in sagittal plane. Menisci of all subjects were also evaluated using semiquantitative MRI OA Knee Score (MOAKS). The results show that the length of $$$AdT_{1\rho}$$$ and $$$AdT_{2\rho}$$$ is directly related to clinical symptoms and the severity of meniscal degeneration. $$$AdT_{1\rho}$$$ and $$$AdT_{2\rho}$$$ may provide a non-invasive means of detecting and monitoring degenerative changes in the meniscus.

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