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Abstract #0380

Improved spiral chemical shift imaging at 3 Tesla using a 32-channel integrated RF-shim coil array

Eren Kizildag1, Jason P Stockmann2, Borjan Gagoski2,3,4, Bastien Guerin2,4, P. Ellen Grant2,3,4, Lawrence L. Wald2,4, and Elfar Adalsteinsson1,5,6

1Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 2A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 3Boston Children’s Hospital, Boston, MA, United States, 4Harvard Medical School, Boston, MA, United States, 5Harvard-MIT Health Sciences and Technology, Cambridge, MA, United States, 6Institute for Medical Engineering and Science, Cambridge, MA, United States

Severe B0 inhomogeneity manifests itself in the in vivo brain Chemical Shift Imaging (CSI) by broadening the lineshapes and diminishing the quality of the observed spectra. We mitigate this problem by employing a 32-channel integrated RF-shim coil array which uses an optimal combination of local B0 fields from each coil to cancel higher order local field inhomogeneities in the CSI volume. We observed 50% reduction in ΔσB0 over the slab as compared with 2nd order shimming, corresponding to pronounced improvements in the linewidths of 13 out of 24 CSI voxels while modestly worsening in only 3 voxels.

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