Abstract #0380

Improved spiral chemical shift imaging at 3 Tesla using a 32-channel integrated RF-shim coil array

Eren Kizildag¹, Jason P Stockmann², Borjan Gagoski^2,3,4, Bastien Guerin^2,4, P. Ellen Grant^2,3,4, Lawrence L. Wald^2,4, and Elfar Adalsteinsson^1,5,6

¹Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ²A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ³Boston Children’s Hospital, Boston, MA, United States, ⁴Harvard Medical School, Boston, MA, United States, ⁵Harvard-MIT Health Sciences and Technology, Cambridge, MA, United States, ⁶Institute for Medical Engineering and Science, Cambridge, MA, United States

Severe B₀inhomogeneity manifests itself in the in vivo brain Chemical Shift Imaging (CSI) by broadening the lineshapes and diminishing the quality of the observed spectra. We mitigate this problem by employing a 32-channel integrated RF-shim coil array which uses an optimal combination of local B₀ fields from each coil to cancel higher order local field inhomogeneities in the CSI volume. We observed 50% reduction in ΔσB₀ over the slab as compared with 2nd order shimming, corresponding to pronounced improvements in the linewidths of 13 out of 24 CSI voxels while modestly worsening in only 3 voxels.

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