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Abstract #0406

Comparison of Conventional DCE-MRI and a Novel Golden-Angle Radial Compressed-Sensing and Parallel Imaging Method for the Evaluation of Breast Lesion Conspicuity and Morphology

Laura Heacock1, Yiming Gao1, Samantha Heller1, Amy Melsaether1, Sungheon Kim1,2, and Linda Moy1

1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 2Center for Advanced Imaging Innovation and Research (CAI2R), New York University School of Medicine, New York, NY, United States

GRASP DCE-MRI (Golden-angle Radial Sparse Parallel) DCE-MRI allows simultaneous high spatial and temporal resolution. The purpose of this study was to evaluate breast lesion conspicuity between GRASP and conventional Cartesian sampling DCE-MRI. Readers assessed conspicuity of 48 biopsy-proven lesions on conventional DCE-MRI and subsequent GRASP biopsy. No significant difference was found between the two techniques for all lesions (p=0.21, p=0.19, p=0.46), masses (p=1.0, p=0.48, p=0.7) or NME (p=0.18,p=0.08, p=0.64). There was strong reader agreement in evaluating conspicuity (ICC=0.735). GRASP DCE-MRI is comparable to conventional DCE-MRI imaging for masses and NME with diagnostic-quality high spatial resolution and flexibility of temporal resolution.

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