Abstract #0461

Towards a quantitative MRI-based measure of disease burden in patients with atrial fibrillation

Maurce Pradella¹, Sven Knecht², Michael Kühne², Aline Mühl², Tobias Reichlin², Gian Voellmin², David Conen², Jens Bremerich¹, Stefan Osswald², Christian Sticherling², and Bram Stieltjes¹

¹Department of Radiology, University of Basel Hospital, Basel, Switzerland, ²Department of Cardiology, University of Basel Hospital, Basel, Switzerland

Atrial fibrillation (AF) is a common disease and associated with myocardial infarction, stroke and dementia. We propose a new approach based on the sphericity of fitted ellipsoids in left atriums of patients with AF. Our results show a strong correlation between sphericity of these ellipsoids and burden of disease and may serve as an objective surrogate parameter in the future.

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