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Abstract #0461

Towards a quantitative MRI-based measure of disease burden in patients with atrial fibrillation

Maurce Pradella1, Sven Knecht2, Michael Kühne2, Aline Mühl2, Tobias Reichlin2, Gian Voellmin2, David Conen2, Jens Bremerich1, Stefan Osswald2, Christian Sticherling2, and Bram Stieltjes1

1Department of Radiology, University of Basel Hospital, Basel, Switzerland, 2Department of Cardiology, University of Basel Hospital, Basel, Switzerland

Atrial fibrillation (AF) is a common disease and associated with myocardial infarction, stroke and dementia. We propose a new approach based on the sphericity of fitted ellipsoids in left atriums of patients with AF. Our results show a strong correlation between sphericity of these ellipsoids and burden of disease and may serve as an objective surrogate parameter in the future.

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