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Abstract #0504

Gradient echo signal decay of bone material at high field requires a gaussian augmentation of the mono-exponential model for T2* determination

Weiqiang Dou1 and Arend Heerschap1

1Radiology, Radboud University Medical Centre, Nijmegen, Netherlands

Previously reported T2*quantification for calcium phosphate cement (CPC), a widely used bone material, remained unsatisfactory with a mono-exponential (ME) fit. A recently proposed Gaussian augmentation of the mono-exponential (GAME) model was reported to have robust fit for gradient echo (GRE) signals. To accurately evaluate GRE-signal decay of CPC, GAME and ME fits were applied in this study for multi-echo time GRE signals acquired at 11.7T. Compared to ME, GAME showed optimal fitting with significantly smaller sum of squared errors and larger R-squared values. Therefore, GAME model is demonstrated to be suitable for GRE signal modeling in CPC at ultra-high field.

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